(Z)-4-[4-(Dimethylamino)benzylidene]-3-methylisoxazol-5(4H)-one
نویسندگان
چکیده
The title compound, C(13)H(14)N(2)O(2), an isoxazol-5-one derivative, was synthesized by a one-pot, three-component condensation reaction of methyl acetoacetate, hydroxy-lamine hydro-chloride and 4-(dimethyl-amino)benzaldehyde. All the non-H atoms are co-planar [r.m.s deviation = 0.0039 Å], with a Z configuration about the C=C bond. The dihedral angle between the phenyl ring and the isoxazole ring is 2.58 (19)°.
منابع مشابه
(Z)-4-Benzylidene-3-methylisoxazol-5(4H)-one
In the title compound C(11)H(9)NO(2), the phenyl and isoxazole rings are almost coplanar, making a dihedral angle of 1.14 (9)°. This planarity is also assisted by an intra-molecular C-H⋯O hydrogen bond between the phenyl ring and the carbonyl O atom. In the crystal, weak C-H⋯O inter-actions generate a layered structure parallel to the ac plane.
متن کاملN-[4-(Dimethylamino)benzylidene]-4H-1,2,4-triazol-4-amine
The title compound, C(11)H(13)N(5), is a Schiff base synthesized by the reaction of 4-amino-4H-1,2,4-triazole and 4-(dimethyl-amino)-benzaldehyde. The dihedral angle between the benzene and triazole rings is 43.09 (11)°. The crystal structure displays weak C-H⋯N inter-actions.
متن کامل1-[4-(Dimethylamino)benzylidene]-4-methylthiosemicarbazide
In the title compound, C(11)H(16)N(4)S, an intra-molecular N-H⋯N hydrogen bond generates an S(5) ring. In the crystal, inversion dimers linked by pairs of N-H⋯S bonds occur, generating an R(2) (2)(8) loop.
متن کاملOrthorhombic modification of (E)-4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one: whole molecule disorder
The title mol-ecule, C(16)H(11)NO(2), is disordered about a pseudo-twofold rotation axis that approximately bis-ects the mol-ecule along the C=O double bond. The two overlapping components are planar [r.m.s. deviation = 0.10 Å in the major 0.537 (4) component and 0.07 Å in the minor component]. The two components are aligned at 1.8 (3)°.
متن کامل(E)-N′-[4-(Dimethylamino)benzylidene]-2-methoxybenzohydrazide
In the title compound, C(17)H(19)N(3)O(2), the two benzene rings form a dihedral angle of 89.2 (2)°. In the crystal structure, mol-ecules are linked through N-H⋯O hydrogen bonds, forming C(4) chains running along the c axis.
متن کامل